We have not used them yet because we haven't went anywhere far that we needed them. My oldest is 11 and has been car sick since she was 1. What I love most about these dramamine pills is that they are capsules and we can open them and put the powder on a spoon, or into food or drink. My daughter has refuses to swallow pill so that is a big bonus. I have never found a dramamine pill that you could take without swallowing a pill.